Research Use Only: This product is supplied for laboratory research and in-vitro studies. Not for human or veterinary administration.
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Selank 10mg
- Synthetic Tuftsin Analogue: Heptapeptide Thr-Lys-Pro-Arg-Pro-Gly-Pro, developed Russian Academy of Sciences, tuftsin core + Pro-Gly-Pro extension for metabolic stability, 20+ years research
- Multi-Modal Mechanism: Positive allosteric modulator of GABA-A receptors, upregulates BDNF (hippocampus/cortex), inhibits enkephalinase (IC50 15 μM), modulates monoamines, no tolerance/dependence
- Clinical Status: Russian FDA approved 2009 for GAD/neurasthenia (intranasal 0.15%), RCT showed efficacy equal to medazepam with additional nootropic effects, no sedation/amnesia unlike benzodiazepines
- Mechanistic pathway studies
- In vitro receptor profiling
- HPLC verified identity and purity
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Research Overview
Selank is a synthetic heptapeptide structurally derived from the endogenous peptide tuftsin. In laboratory research, Selank is studied as a molecular probe for investigating neurochemical signaling, gene expression regulation, and peptide-mediated modulation of immune and neuroendocrine pathways. Experimental studies focus on its biochemical interactions in controlled cellular systems and in vivo animal models.
Preclinical Research Summary
Preclinical studies involving Selank have primarily utilized rodent models and in vitro biochemical systems. Published data describe changes in transcriptional profiles of neural and immune tissues, including genes associated with inflammatory signaling, neurotransmitter receptor modulation, and stress-responsive pathways.
Animal-based experiments have further evaluated Selank as a tool for studying peptide-mediated regulation of gene networks involved in neuroimmune communication. These investigations emphasize pathway-level observations rather than organism-level outcomes.
This product is intended exclusively for in vitro laboratory research by qualified professionals. Not for human consumption. Not approved by the FDA.
Published Research Briefs
Our research team has published evidence-checked briefs covering the science behind this compound. Each brief reviews primary sources and grades claims independently.