Oxytocin (2 mg)

Oxytocin (2 mg) Research Peptide Molecular Profile: Oxytocin is a cyclic nonapeptide with the sequence Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH₂. Molecular formula C₄₃H₆₆N₁₂O₁₂S₂, molecular weight 1007.19 Da, CAS 50-56-6. The disulfide bridge between Cys¹ and Cys⁶ creates a six-membered cyclic structure essential for receptor binding and biological activity. Mechanism of Action: Oxytocin functions as a selective agonist for the oxytocin receptor (OXTR), a G protein-coupled receptor that preferentially couples to Gαq/11 proteins. OXTR activation stimulates phospholipase C (PLC), which hydrolyzes PIP₂ to generate IP₃ and DAG second messengers. IP₃ triggers Ca²⁺ release from intracellular stores, while DAG activates protein kinase C. This Gq/11-PLC-Ca²⁺ signaling cascade mediates oxytocin's diverse physiological and behavioral effects. The receptor also demonstrates coupling to Gi/Go proteins, enabling context-dependent signaling outcomes. Research Applications: Oxytocin serves as a critical research tool for investigating GPCR signaling mechanisms, social behavior neuroscience, reproductive physiology, neuroendocrine integration, and translational approaches to social cognition disorders. The peptide enables studies of phosphoinositide signaling, calcium mobilization, neural circuit modulation, and precision medicine biomarker development. Product Specifications: Research-grade oxytocin supplied as lyophilized powder, >99% purity verified by HPLC with batch-specific Certificates of Analysis. Store lyophilized product at -20°C for optimal long-term stability (3-5 years). Upon reconstitution with sterile water or bacteriostatic water, refrigerate solutions at 2-8°C for up to 28-30 days. Protect from light, moisture, and oxidative conditions. The disulfide bridge is sensitive to pH and temperature; acidic storage conditions (pH 3-4) enhance stability. Laboratory Use Disclaimer: FOR RESEARCH AND LABORATORY USE ONLY. NOT FOR HUMAN OR VETERINARY USE. This product is intended solely for research applications by qualified investigators in controlled laboratory settings. Not approved for human consumption, clinical applications, therapeutic use, or veterinary medicine. Researchers must comply with all applicable institutional, local, state, and federal regulations. Proper laboratory safety protocols must be observed. Disposal must follow institutional chemical waste procedures.